Soft Tissue Sarcoma Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

Metastatic Leiomyosarcoma (LMS)

Lurbinectedin + doxorubicin

IIb/III

Open, recruiting

PharmaMar

Advanced or metastatic Soft Tissue Sarcoma

Onfekafusp alfa (L19TNF) + Doxorubicin vs. Doxorubicin alone

III

Open, recruiting

Philogen S.p.A.

Soft Tissue Sarcoma

M2554

I

Open, recruiting

EMD Serono Research & Development Institute, Inc.

Synovial sarcoma and myxoid/round cell liposarcoma (MRCLS)

DS-2243a

I

Open, recruiting

Daiichi Sankyo

Advanced Pediatric Solid & CNS Tumors

LOXO-292

I/II

Open, recruiting

Loxo Oncology, Inc. (Eli Lilly)

Solid tumors incl. soft tissue sarcomas

AVA6000

I

Open, recruiting

Avacta Life Sciences Ltd.

Advanced solid tumors incl. EHE

IAG933

I

Open, recruiting

Novartis Pharmaceuticals

Epithelioid Sarcoma

Tazemetostat + doxurubicin vs. docurubicin + placebo

III

Open, recruiting

Epizyme Inc.

Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Gene therapy: ADP-A2M

II

Open, recruiting

Adaptimmune

Solid tumors incl. soft tissue and bone sarcomas

TNG462

I/II

Open, recruiting

Tango Therapeutics

Leiomyosarcoma & Liposarcoma

Preoperative chemotherapy & surgery

III

Open, recruiting

EORTC

Advanced or Metastatic Soft-tissue Sarcoma

Dacarbazine + L19TNF

II

Open, recruiting

Philogen S.p.A.

Extremity Soft Tissue Sarcomas

Preoperative Radiotherapy

II

Open, recruiting

The Netherlands Cancer Center

Solid tumors incl. soft tissue and bone sarcomas

TNG908

I/II

Closed for recruitment

Tango Therapeutics

Liposarcoma

BI 907828

III

Closed for recruitment, but active

Boehringer Ingelheim