Bone Sarcoma Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

Conventional chondrosarcoma

INBRX-109 vs. placebo

II

Open, recruiting

Inhibrx, Inc.

Ewing's sarcoma

Different chemotherapy regimens

II/III

Open, recruiting

University of Birmingham

Osteosarcoma

Cabozantinib

II

Open, recruiting

Ipsen

Conventional chondrosarcoma

Ivosidenib vs. placebo

III

Open, recruiting

Servier Bio-Innovation LLC

Ewing Sarcoma / SDH-deficient GIST

INBRX-109

I

Open, recruiting

INHIBRX Inc.

Ewing's sarcoma, Chondrosarcomas, Osteosarcomas, Chondromas

Regorafenib vs. placebo

II

Open, recruiting (France only)

UNICANCER

Ewing Sarcoma in children/young adults

Lurbinectedin

I/II

Open, recruiting

Jazz Pharmaceuticals

Solid tumors incl. soft tissue and bone sarcomas

TNG462

I/II

Open, recruiting

Tango Therapeutics

Ewing's Sarcoma

Abemaciclib (LY2835219) + Irinotecan + Temozolomide

II

Open, recruiting

Eli Lilly and Company

Ewing Sarcoma / Pediatric Patients

Palbociclib in combination with chemotherapy

II

Closed for recruitment, but active

Pfizer

Solid tumors incl. soft tissue and bone sarcomas

TNG908

I/II

Closed for recruitment

Tango Therapeutics