Register now: SPAGN Annual Conference & New Horizons GIST 2023

Register now! 2023 SPAGN Annual Conference May 11-13, 2023 in Dublin/Ireland NEW HORIZONS GIST May 13-15, 2023 in Dublin/Ireland For the first time ever, the SPAGN Annual Conference and the New Horizons GIST Meeting will be held hand in hand. Since 2010, SPAEN/SPAGN has organized the SPAEN/SPAGN Annual Conferences to bring sarcoma, GIST and desmoid…

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Mantra-2: Milademetan in advanced/metastatic solid tumors incl. sarcomas

  Agents: Milademetan Phase II Status Recruiting Sponsor Rain Oncology   For further information please also consult ClinicalTrials.gov.   This is a phase II basket study that evaluates the safety and efficacy of milademetan in patients with advanced or metastatic solid tumors with specific mutations (wild-type (WT) TP53 or MDM2) after standard-of-care therapy.   WHO…

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TNG908 in MTAP-deleted solid tumors including soft tissue and bone sarcomas

Safety and tolerability of TNG908 in MTAP-deleted solid tumors including sarcomas Agents: TNG908 Phase I/II Status Closed for recruitment Sponsor Tango Therapeutics   Further information on Clinicaltrials.gov.   Phase I/II study in solid tumor patients with a specific genetic mutation, a MTAP deletion, including sarcomas (soft tissue and bone sarcomas) WHO is the trial for?…

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Looking back on 2022 and ahead to 2023

How was 2022 for your organization? What accomplishments are you proud of?

We at SPAGN are looking back at what we have done in the past year to impact the treatment and survival of sarcoma patients. We also want to look ahead to our plans for the near future.

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Spain: Sarcoma Patients Spanish Association/Asociación Española de Afectados por Sarcoma (AEAS)

Asociación Española de Afectados por Sarcoma (AEAS)   Contact Information Email: secretaria@aeasarcomas.org Phone: 0034681301754 Web: https://www.aeasarcomas.eu/       Contact Persons Presidente: Jose Luis Muñoz Vicepresidente: Dr. Antonio Casado Secretario: Orlando Dámaso   Organisation profile AEAS, the Sarcoma Patients Spanish Association, is a non profit organization that advocates on behalf of people affected by sarcoma.…

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IDRX-42 in metastatic and/or unresectable GIST

  Trial name: IDRX in advanced GIST Agents: IDRX-42 Phase I/Ib Status Recruiting Sponsor IDRx Inc.   This is a Phase 1/1b open-label study of IDRX-42 in metastatic and/or unresectable GIST. Further information can be found on clinicaltrials.gov.   WHO is the trial for? Adult patients with confirmed diagnosis of unresectable or metastatic GIST Patients…

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SunriseLMS: Unesbulin in Advanced Leiomyosarcoma

  Agents: Unesbulin vs. Placebo Phase II/III Status Recruiting Sponsor PTC Therapeutics   For further information please also consult ClinicalTrials.gov. This study compares the efficacy and safety of unesbulin plus dacarbazine versus placebo plus dacarbazine in advanced LMS who have received at least 1 prior line of systemic therapy.   WHO is the trial for?…

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Brightline-1: Advanced Dedifferentiated Liposarcoma

Treatment of BI 907828 Versus Doxorubicin in Patient With Advanced Dedifferentiated Liposarcoma (Brightline-1) Agents: BI 907828 vs. Doxorubicin Phase II/III Status Closed for recruitment, trial still ongoing (active) Sponsor Boehringer Ingelheim   For further information please also consult ClinicalTrials.gov.   This is a Phase II/III registration study evaluating the safety and efficacy of BI 907828…

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